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There was no difference in demographics, age, duration of PSC, or clinical phenotype (small vs large duct at diagnosis, concomitant AIH or IBD) between patients dichotomized by liver stiffness of 3.29 kPa (Table)

A: Liposomal Glutathione is wrapped in tiny lipid bubbles that protect it during digestion, helping more glutathione reach the bloodstream intact

Dose-dependently improved organ coefficients (reduced liver coefficient, increased cardiac and kidney coefficients) and reduced tissue damage (cardiomyocyte degeneration, kidney glomerular/tubular damage, hepatocyte ballooning, pancreatic islet loss) in db/db mice, with 500 mg/kg treatment more effective than metformin

10.1016/j.jhep.2019.11.017 115 VozzaA.ParisiG.De LeonardisF.LasorsaF